THC for Alcohol Withdrawal: Your Questions, Answered

Alcohol use disorder affects 1 in 10 Americans and contributes to more than 175,000 deaths per year. But, is THC used for alcohol withdrawal symptoms, or help with treating AUD at all?

Finding safe and appropriate treatment options can help you get the help you deserve. Evidence based interventions are the safest and most effective ways to make this journey a little easier.

Key Facts

  • 1 in 10 Americans live with alcohol use disorder; over 175,000 die yearly from related causes.
  • Withdrawal symptoms can start 6–24 hours after the last drink and may become life threatening within 48–96 hours.
  • THC is psychoactive, while CBD is non-intoxicating, and both have been studied for therapeutic effects.
  • No clinical evidence supports THC for acute alcohol withdrawal; guidelines recommend proven medications instead.
  • THC can worsen withdrawal risks, including sedation, anxiety, psychosis, and heart complications.

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Alcohol Withdrawal at a Glance

Alcohol withdrawal can trigger uncomfortable and sometimes serious symptoms as your body adjusts to the absence of alcohol. Understanding how these symptoms develop and the role medications may play is the first step in safely managing the withdrawal process.

Withdrawal Timeline, Symptoms & Red Flags 

A woman lies awake in bed late at night, battling insomnia, which is a common symptom of alcohol withdrawal

Symptoms of alcohol withdrawal can range from mild to life threatening. The onset of symptoms usually occurs between 6-24 hours after the last drink. Symptoms include tremors, anxiety or insomnia.

More serious and potentially life threatening symptoms, including seizures or delirium tremens or DTs, can begin between 12-96 hours after your last drink.

Serious withdrawal symptoms, including confusion, hallucinations, fever, uncontrolled vomiting or chest pain, should be evaluated immediately by a medical professional. 

Detox can occur in an inpatient or outpatient setting, including at home. Determining the appropriate level of care to safely detox depends on factors like the severity of addiction and withdrawal symptoms, co-occurring medical or psychiatric conditions and availability of support systems. 

THC & CBD Basics for Context

THC and CBD are two of the most recognized compounds found in cannabis, each interacting with the body’s endocannabinoid system in different ways.

While THC is known for its psychoactive effects, CBD is non-intoxicating. Both have been studied for potential therapeutic benefits.

THC vs CBD, Products & Dosing Basics

Marijuana containing products have many different phytocannabinoids that act on the body’s endocannabinoid system. The two primary phytocannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). 

Our endocannabinoid system is responsible for maintaining balance in areas that regulate appetite, sleep, mood and the immune system. THC activates the CB1 receptors in the body. It is a psychoactive compound, causing feelings of euphoria, relaxation and altered perception.

CBD activates the CB2 receptors in the body. It is a non intoxicating compound, and has anti-inflammatory, analgesic and anti-anxiety properties. The full marijuana plant can be used in several forms, including flower or vapes, edibles or beverages and tinctures. The onset and duration of action depend on how it is ingested. 

When cannabis is smoked, the effects can be felt within minutes and can wear off relatively quickly, whereas when consumed by eating or drinking, the onset of action is much longer, between 30 minutes and 2 hours and takes longer for the effects to wear off.

Potency can also differ between the different strains of marijuana and how it is produced. This means that it is difficult to manage how use will impact alcohol withdrawal symptoms. 

Does THC Help With Alcohol Withdrawal?

There are no human clinical trials that support the use of THC for acute alcohol withdrawal. In fact, major alcohol withdrawal treatment guidelines recommend it is not used.

What the Research & Guidelines Say

Most current research and guidelines recommend the use of evidenced based pharmacotherapy along with close monitoring for the treatment of acute alcohol withdrawal.

The use of THC to aid the withdrawal process is experimental in this context. 

Cannabis Alcohol Patterns & the “Cali Sober”/ THC Drinks Trend

There is mixed data on the efficacy of using THC to help during acute alcohol withdrawal.

Cali sober is an informal termthat is used when a person stops using alcohol and other hard drugs but continues to use THC. Some people perceive this as a safer alternative with a reduced risk of overdose.

Many addiction professionals do not support this form of “sobriety” because it can potentially trade one addictive behavior for another and increase the risk of relapse.

THC drinks have become a popular treatment for alcohol withdrawal relief, especially among millennials and Gen Z.

While THC can help to ease some of the alcohol withdrawal symptoms, especially nausea, some research indicates that the psychoactive properties of THC increases anxiety symptoms during withdrawal. 

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Risks, Interactions & Who Should Avoid THC During Withdrawal

While some people explore THC for relief during alcohol withdrawal, it’s important to recognize the potential risks and drug interactions involved. Certain individuals may face greater health concerns, making THC use unsafe in this context.

Sedation & Drug Interactions 

Using THC with medications that cause central nervous system depression, such as benzodiazepines, gabapentin, barbiturates and sleep medication can be dangerous. This increases the risk of a potential overdose or accident.

The potential for overdose increases with concurrent use, resulting from the impact the drugs have on the respiratory and nervous systems. Both drugs can cause drowsiness and depressed respirations, which potentiate each other in unpredictable ways.

Accidents are more likely to occur when THC is combined with other central nervous system depressants since it can result in impaired coordination and poor judgment, leading to falls or accidents.

Psychiatric, Cognitive & Cardiovascular Risks

THC, especially in high doses or concentrates, can cause anxiety, paranoia, panic attacks and an increased risk of psychosis.

Because these symptoms are also common during alcohol withdrawal, THC potentially increases the risk of developing or making symptoms worse. 

Tachycardia, blood pressure shifts and arrhythmia risks can occur during alcohol withdrawal because of dehydration, commonly found during alcohol withdrawal. Using THC increases the risk of developing these symptoms.

Who Should Not Use THC During Withdrawal

THC is typically not appropriate for people going through alcohol withdrawal, as it can worsen certain health conditions or interact with medications.

It may be best to avoid using THC during this time if you:

  • Use a sedative detox regimen
  • Have psychosis or severe mood disorder history
  • Have heart disease
  • Are pregnant or breastfeeding
  • Are an adolescent or young adult related to the impact on neurodevelopment
  • Have a history of cannabis use disorder
  • Have a strong family history of psychosis 

What to Do Instead (Evidence Based Care)

A doctor speaks with a patient during an alcohol withdrawal assessment

There are several evidence based care options when you’re experiencing acute alcohol withdrawal that do not include THC. 

Withdrawal Management Essentials (What Works) 

Research has found that the safest and most effective way to treat acute alcohol withdrawal is using qualified medical professionals to assess withdrawal symptoms using the Clinical Institute Withdrawal Assessment for alcohol or CIWA-Ar.

This allows substance use professionals to monitor the severity of alcohol withdrawal symptoms at regular intervals. 

Interventions are informed by the CIWA-Ar score. These interventions can include:

  • System triggered benzodiazepines treatment 
  • Continued close monitoring 
  • Seizure and delirium tremens (DT) precautions 
  • Correcting fluid and electrolyte balance 
  • Creating a plan that encourages healthy sleep habits

Individuals who choose to use cannabis to treat their acute alcohol withdrawal symptoms should:

  • Avoid any sedatives with THC
  • Use only low dose THC/CBD combination substances
  • Practice extreme caution with dosing since strains of THC have differing levels of potency
  • Stop THC if confusion, chest pain or severe anxiety emerges and seek immediate medical treatment

After Detox Treatment Options for AUD

Detox is the first step toward long lasting and sustainable recovery. A life in sobriety requires continued therapy, counseling, relapse prevention planning and aftercare. Medication assisted treatment, such as with naltrexoneacamprosate, disulfiram, or topiramate, depends on your unique treatment needs.

Treatment typically includes therapies such as cognitive behavioral therapy (CBT) or motivational enhancement therapy (MET) to help identify the underlying causes of addiction. This includes creating healthier coping skills and behaviors that support long term recovery and develop interventions to prevent relapse. 

Mutual help groups and recovery support services such as Alcoholics Anonymous or SMART Recovery can provide support and understanding from peers who understand the struggles of making change and staying sober.

THC for Alcohol Withdrawal FAQs

Can THC Replace Benzodiazepines for Alcohol Withdrawal?

No, there is no evidence that THC treats acute alcohol withdrawal, while benzodiazepine use is a proven first line intervention with proven seizure and DT risk reduction.

Is CBD a Safer Alternative for Managing Withdrawal? 

CBD is not effective for acute withdrawal and is not a substitute for guideline based detox.

Are THC Drinks a Good Way to Taper Off Alcohol?

THC has not been proven to effectively treat withdrawal, in part because of the variability in dosing and onset of action. The long duration of oral THC increases the risk of over intoxication and interactions with other substances. 

Find Treatment Near You

Taking the first step toward a life in recovery is one of the best decisions you can make. Rehab.com offers an online databasewhere you can find the treatment program that is best for you.

You can filter treatment centers by location, level of care, insurance coverage and special program services.

Not sure where to start? Call 800-985-8516 ( Question iconSponsored Helpline ) today to talk to someone about your treatment options and see if your insurance will cover rehab. 

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